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Diagnostic considerations


AL amyloidosis is a multifaceted disease that requires many considerations. Find out about the potential factors and tests for patients with suspected AL amyloidosis and how to subtype patients once a positive AL amyloid biopsy has been obtained.


Disclaimer: The information in this section is being provided for educational purposes and is not intended to suggest or recommend any manner or method of diagnosis or treatment.


Considerations/tests for AL Amyloidosis
Sub-typing AL amyloidosis

Here are the various factors and tests to consider when AL amyloidosis is suspected.[1][2][3][4][5][6][7]

Multiple organ and tissue involvement raise suspicion of AL amyloidosis

Multiple organ and tissue involvement raise suspicion of AL amyloidosis

DPD=3,3-diphosphono-1,2-propanodicarboxylic acid; PYP=pyrophosphate; TTR=transthyretin.

Learn about AL amyloidosis
Learn about the steps involved in diagnosing patients with AL amyloidosis

Download this information on AL amyloidosis

References

Desport E, et al. Orphanet J Rare Dis. 2012;7:54.
Merlini G, et al. Nat Rev Dis Primers. 2018;4(1):38.
Gertz MA, et al. Nat Rev Cardiol. 2015;12(2):91–102.
Vaxman I and Gertz M. Acta Haematol. 2019;141(2):93–106.
Kapoor M, et al. J Neuromuscul Dis. 2019;6(2):189–99.
Bokhari S, et al. J Nucl Cardiol. 2014;21(1):175–84.
Connors LH, et al. Circulation. 2016;133(3):282–90.
CP-255639 - September 2021